Beneficial Effects of Sulforaphane-Yielding Broccoli Sprout on Cardiometabolic Health: A Systematic Review and Meta-Analysis

Context: Cruciferous vegetables are among the popular functional foods in disease prevention and health promotion. Emerging literature suggest that Sulforaphane-yielding broccoli sprouts can influence cardiometabolic diseases management. Objectives: Given increasing prevalence of worldwide, this systematic review meta-analysis aimed to study implications sprout supplementation within literature. Methods: Eligible was retrieved through Pubmed Scopus up June 2022. Results: Ten clinical trials investigating human subjects were extracted for meta-analysis. The earliest published 2004, most recent released 2019. Seven studies included control groups valid comparison. Overall, dietary intake significantly reduced systolic (-10.9 mmHg; 95% confidence interval (CI): -17.0, -4.86) diastolic (-6.95 CI: -10.6, -3.28) blood pressures. Marginally significant changes also detected lipid biomarkers compared baseline. Conclusions: Our results confirm hypotensive properties highlight potential sulforaphane-dependent effects vegetable.